Endocrine Abstracts

Introduction: Primary hyperthyroidism relates to the thyroid gland producing large amounts of hormone due to either uncontrolled growth of hormone-producing functional tissue. This condition needs to be treated surgically in order to prevent complications.Objective: The aim of this study is to describe the surgical treatment of primary hyperparathyroidism.Method: This is a retrospective study of 84 patients operated on for pimary h...

Introduction: Papillary carcinoma is the most common histological type of thyroid carcinomas. Lymph node involvement is an important prognostic factor. But its management remains uncodified.Objective: The aim of our study was to identify the predictive factors of lateral lymph node metastases in papillary thyroid carcinoma.Methods: This is a retrospective study including 96 patients operated on for papillary thyroid carcinoma at ou...

Introduction: Papillary cancer accounts for 90 % of all thyroid cancers. Although this cancer has a good prognosis, some patients do not respond well to the conventional treatment (surgery and iodine radiation therapy).Objective: The aim of this study is to identify predictive factors of persistent or refractory disease in papillary thyroid cancer.Method: This is a retrospective study including 79 patients who underwent surgery for...

Introduction: Carcinogenesis results from a disturbance in the balance between apoptosis and cell proliferation. This process involves inflammatory cells, which play a pro- and anticarcinogenic role.Objective: the aim of this study is to investigate the status of neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) as potential biomarkers in predicting the evolutionary profile of papillary thyroid cancers.Methods: ...

Introduction: Parathyroid cysts (PCs) are uncommon lesions. They represent less than 0.5% of parathyroid lesions. Cysts are divided into two groups, functional and non-functional, in relation to their hormonal characteristics. Non-functioning ones make up 80 – 90% of PCs.We discussed three cases of non-functioning parathyroid cysts that we surgically excised.Methods: We report 3 cases of non-functioning PCs treated in our department.<p class="ab...

Introduction: In 80–90% of cases, the cause of sporadic primary hyperparathyroidism is adenoma of one parathyroid gland. Multiple-gland disease (MGD) is defined in patients with more than one pathological parathyroid gland. The frequency of occurrence of MGD is from 7% to 33%.Our aim is to report a case of primary hyperparathyroidism with MGD and to describe its diagnostic and therapeutic features.Case Report: A 55-year-old man presented with 1-year...

Introduction: Intraoperative management of thyroid gland in laryngeal cancer is controversial. In fact, there is no uniform consensus about the need for thyroid surgery in laryngeal cancer.Objective: Determine the incidence of thyroid gland invasion in patients undergoing surgery for laryngeal squamous cell carcinoma.Methods: A retrospective study including 62 cases of laryngeal squamous cell carcinoma who underwent a total larynge...

Introduction: Primary mucinous carcinoma of the thyroid gland is extremely rare. To the best of our knowledge, only nine cases have been reported in the literature. Our aim is to report a case of primary mucinous carcinoma of the thyroid gland and to describe its diagnostic and prognostic features.Case Report: A 55-year-old man referred to our department for a 2-month history of an anterior neck mass associated with dysphagia. Physical exam showed a 4-cm...

Introduction: Anaplastic thyroid carcinoma (ATC) is rare. This highly aggressive malignant tumor accounts for 2 – 3 % of all thyroid gland neoplasms. ATC continues to be one of the deadliest diseases worldwide and carries a very poor prognosis. The aim of this study was to describe the treatment modalities of ATC and its prognostic features.Methods: A retrospective study of patients with ATC treated in our department between 2004 and 2021.<p cla...

Introduction: Oncocytic tumors can occur in the thyroid gland and other endocrine tissues, including the parathyroid, pituitary gland, adrenal cortex, pancreas, gut, and lung. Thyroid oncocytic tumors are rare: 3-10% of thyroid epithelial tumors. They are characterized by the presence of oncocytic cells called “Hürthle” cells.Objective: Describe the clinical, pathological and therapeutic features of oncocytic tumors of the thyroid gland.</...